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Most children with severe inflammatory bowel disease have had mild COVID

The majority of children with severe coronavirus-related inflammatory disease have had an initial COVID-19 infection with no symptoms or only mild, according to a new US study.

The unusual post-infectious condition is milder in children who were more likely to have COVID-19 despite more than half of those affected receiving intensive hospital care, according to an analysis by the Federal Center for Disease Control and Prevention released by JAMA Pediatrics on Tuesday. to whom? ,

The study is the largest analysis of multidisciplinary inflammatory syndrome in children in the United States to date and supports evidence that it is a delayed immune response to COVID-19. The study included nearly 1,800 cases reported to the CDC between March 2020 and mid-January. Most were in children under 15 years of age, but the study included up to 20 years of age.

The researchers say the increase in cases occurred two to five weeks after the peak of COVID-19, following the spread of primary infections from urban to rural areas. Recent data from the CDC show that there is a new peak in pediatrics in line with this trend.

The number of deaths reported by the state as of March 29 was 3,185, including 36 deaths, according to the CDC website. Government reports are not always on time, so it is unclear how many children in the United States have fallen ill since the study was completed.

Most children with COVID-19 do not have post-infectious disease. According to the American Academy of Pediatrics, the Association of Children’s Hospitals, nearly 3.5 million US children and adolescents tested positive for COVID-19.

This situation was first reported in Europe in the late spring of last winter. Some cases, especially those that follow silent, undetected COVID-19 infections, can be mistaken for Kawasaki disease, a rare condition that can cause redness of the skin, swelling, and heart problems.

Dr. Sean O’Leary, vice president of the Infectious Diseases Committee at the Academy of Pediatrics, says that inflammatory conditions usually make children sick very quickly, but most of them “respond very well to treatment; the vast majority recover completely.” «

Treatment may include steroids or other medications that can reduce inflammation.

The best way to prevent this is to prevent COVID-19 infections, “which vaccines do very well,” he said. COVID-19 vaccine studies in children are ongoing.

In the CDC analysis, fever was one of the most common symptoms. Abdominal pain, vomiting, diarrhea և Redness of the skin A skin rash has occurred in at least half of the affected children. Nearly one-third had heart disease or other heart involvement. These symptoms were least common in children under 4 years of age, who were also more likely to need intensive care than older children.

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Follow AP Medical Writer Lindsey Tanner at @LindseyTanner.

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The Associated Press Department of Health and Science receives support from the Department of Science Education at Howard Hughes Medical Institute. The AP is solely responsible for all content.

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